2021

2021

Biophytis BIO101 in Sarcopenia: Lessons learned from the SARA program. Tourette C., Dioh W., Margalef C., Azbekyan A., Rabut S., Dupont P., Lafont R., Dilda P., Mariani J., Del Signore S., Agus S., Veillet S. Orally presented at ICFSR 2021, Sept 29^th – Oct 2^nd. The Journal of Frailty & Aging, in press

In vivo effects of Sarconeos (API BIO101) on a mouse model of severe spinal muscular atrophy. Bézier C., Cottin S., Dilda P., Lafont R., Veillet S., Charbonnier F., Latil M., Biondi O. Online poster presented at the 26^th WMS virtual annual Congress, 20-24^th September, Neuromuscular Disorders, Vol. 31: S131.

Sarconeos (API BIO101) improves outcomes in a mouse model of severe spinal muscular atrophy. Bézier C., Nazari Hashemi P., Cottin S., Lafont R., Veillet S., Charbonnier F., Dilda P., Latil M., Biondi O. Poster presented at 18^th Journée de la Société Française de Myologie. 24-26^th November, Saint-Étienne, France

A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortality. Camelo S., Latil M., Agus S., Dioh W., Veillet S., Lafont R., Dilda P.J. Article published in Emerging Microbes and Infections, 10 (1): 2256-2263. https://doi.org/10.1080/22221751.2021.2006579.

Preclinical efficacy of BIO101 on respiratory function in SARS-CoV-2-infected Syrian hamsters. Latil et al. Poster presented at 31^st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID). 9-12^th July 2021.

Ecysteroid metabolism in mammals: the fate of ingested 20-hydroxyecdysone in mice and rats. Dinan et al. Article published in Journal of Steroid Biochemistry and Molecular Biology, 212: 105896. https://doi.org/10.1016/j.jsbmb.2021.105896.

The complex metabolism of poststerone in male rats. Balducci et al. Published in Journal of Steroid Biochemistry and Molecular Biology. 212: 105897. https://doi.org/10.1016/j.jsbmb.2021.105897.

Testing the efficacy and safety of BIO101, for the prevention of respiratory deterioration, in patients with COVID-19 pneumonia (COVA study): a structured summary of a study protocol for a randomized controlled trial. Dioh et al. Article published in Trials, 22:42.

20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases. Dinan et al. Article published in Biomedicines, 9 (5): 492. doi: 10.3390/biomedicines9050492.

Developing new drugs activating the protective arm of the Renin Angiotensin System as a potential treatment of respiratory failure in COVID-19 patients. Latil et al. Article published in Drug Discovery Today, 26 (5), 1311-1318.